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Structure of PDB 1yvp Chain B Binding Site BS01

Receptor Information >1yvp Chain B (length=532) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] TMDQTQPLNEKQVPNSEGCYVWQVSDMNRLRRFLCFGSEGGTYYIEEKKL GQENAEALLRLIEDGKGCEVVQEIKTFSQEGRAAKQEPTLFALAVCSQCS DIKTKQAAFRAVPEVCRIPTHLFTFIQFKKDLKEGMKCGMWGRALRKAVS DWYNTKDALNLAMAVTKYKQRNGWSHKDLLRLSHIKPANEGLTMVAKYVS KGWKEVQEAYKEKELSPETEKVLKYLEATERVKRTKDELEIIHLIDEYRL VREHLLTIHLKSKEIWKSLLQDMPLTALLRNLGKMTADSVLAPASSEVSS VCERLTNEKLLKKARIHPFHILVALETYKKGHGNKLRWIPDTSIVEALDN AFYKSFKLVEPTGKRFLLAIDVSASMNQRVLGSILNASVVAAAMCMLVAR TEKDSHMVAFSDEMLPCPITVNMLLHEVVEKMSDITMGSTDCALPMLWAQ KTNTAADIFIVFTDCETNVEDVHPATALKQYREKMGIPAKLIVCAMTSNG FSIADPDDRGMLDICGFDSGALDVIRNFTLDL

Ligand information >1yvp Chain E (length=10) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] gcugguccga ..........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1yvp Structural Insights into RNA Quality Control: The Ro Autoantigen Binds Misfolded RNAs via Its Central Cavity Resolution 2.2 Å Binding residue (original residue number in PDB) K108 Q109 K133 G142 W144 G145 R146 A147 R149 W177 D181 R184 L185 H187 Binding residue (residue number reindexed from 1) K105 Q106 K130 G139 W141 G142 R143 A144 R146 W174 D178 R181 L182 H184 Binding affinity PDBbind-CN: Kd=5.2nM

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003723 RNA binding GO:0034336 misfolded RNA binding GO:0046872 metal ion binding

	Biological Process
GO:0030030	cell projection organization

	Cellular Component
GO:0005737	cytoplasm
GO:1990904	ribonucleoprotein complex

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