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BioLiP

Structure of PDB 7q3o Chain K Binding Site BS01

Receptor Information
>7q3o Chain K (length=61) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKI
WFQNRRAKERK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7q3o Structure of CDX1 bound to hydroxymethylated DNA
Resolution2.78 Å
Binding residue
(original residue number in PDB)		R184 T185 Y189 R190 V191 V192 Y193 R228 Q229 I232 N236 K240
Binding residue
(residue number reindexed from 1)		R2 T3 Y7 R8 V9 V10 Y11 R46 Q47 I50 N54 K58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7q3o, PDBe:7q3o, PDBj:7q3o
PDBsum7q3o
PubMed
UniProtP47902|CDX1_HUMAN Homeobox protein CDX-1 (Gene Name=CDX1)

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