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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Urotensin-2 receptor
Species	Mus musculus (Mouse)
Gene	Uts2r
Synonym	UT receptor Urotensin II receptor UR-II-R UR-2-R UII-R1 SENR (sensory epithelial neuropeptide-like receptor) GPR14 G-protein coupled receptor 14 G protein-coupled receptor 14 UTR2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	385
Amino acid sequence	MALSLESTSFPMLAVSRSTASELPGGFNVSHNSSWTGPTDPSSLQDLVATGVIGAVLSTMGVVGVVGNVYTLVVMCRFLRASASMYVYVVNLALADLLYLLSIPFIVATYVTKDWHFGDVGCRVLFSLDFLTMHASIFTLTIMSSERYAAVLRPLDTVQRSKGYRKLLALGTWLLALLLTLPMMLAIRLVRRGSKSLCLPAWGPRAHRTYLTLLFGTSIVGPGLVIGLLYIRLARAYWLSQQASFKQTRRLPNPRVLYLILGIVLLFWACFLPFWLWQLLAQYHQAMPLTPETARIINYLTACLTYGNSCINPFLYTLLTKNYREYLRGRQRSLGSSCRGPGSAGSFLSSRVHLQQDSGRSLSSNSQQATETLVLSPVPPNGAFV
UniProt	Q8VIH9
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2346494
IUPHAR	365
DrugBank	N/A

Ligand

Name	CHEMBL2348502
Molecular formula	C20H23BrClNO5S
IUPAC name	(3R)-3-[5-[(2-bromo-4,5-dimethoxyphenyl)sulfonylmethyl]-2-chlorophenoxy]-1-methylpyrrolidine
Molecular weight	504.82
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.1
Synonyms	BDBM50431963
Inchi Key	SDTZEZIBBCCXPG-CQSZACIVSA-N
Inchi ID	InChI=1S/C20H23BrClNO5S/c1-23-7-6-14(11-23)28-17-8-13(4-5-16(17)22)12-29(24,25)20-10-19(27-3)18(26-2)9-15(20)21/h4-5,8-10,14H,6-7,11-12H2,1-3H3/t14-/m1/s1
PubChem CID	71579743
ChEMBL	CHEMBL2348502
IUPHAR	N/A
BindingDB	50431963
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	4700.0 nM	PMID23453841	BindingDB,ChEMBL

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