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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 6
Species	Homo sapiens (Human)
Gene	P2RY6
Synonym	pyrimidinergic receptor P2Y P2Y6 receptor P2Y6 P2Y purinoceptor 6 P2Y ATP receptor 6 uridine nucleotide receptor [ Show all ]
Disease	N/A
Length	328
Amino acid sequence	MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
UniProt	Q15077
Protein Data Bank	N/A
GPCR-HGmod model	Q15077
3D structure model	This predicted structure model is from GPCR-EXP Q15077.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4714
IUPHAR	326
DrugBank	N/A

Ligand

Name	CHEMBL1084612
Molecular formula	C22H36N4O12P2
IUPAC name	N,N-diethylethanamine;[(2R,3S,4R,5R)-3,4-dihydroxy-5-[2-oxo-4-(phenylmethoxyamino)pyrimidin-1-yl]oxolan-2-yl]methyl phosphono hydrogen phosphate
Molecular weight	610.494
Hydrogen bond acceptor	13
Hydrogen bond donor	6
XlogP	None
Synonyms	MRS-2964
Inchi Key	AEIHJAGESPJDDO-MOAMTLHQSA-N
Inchi ID	InChI=1S/C16H21N3O12P2.C6H15N/c20-13-11(9-29-33(26,27)31-32(23,24)25)30-15(14(13)21)19-7-6-12(17-16(19)22)18-28-8-10-4-2-1-3-5-10;1-4-7(5-2)6-3/h1-7,11,13-15,20-21H,8-9H2,(H,26,27)(H,17,18,22)(H2,23,24,25);4-6H2,1-3H3/t11-,13-,14-,15-;/m1./s1
PubChem CID	46831685
ChEMBL	CHEMBL1084612
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
EC50	2130.0 nM	PMID20446735	ChEMBL

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