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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 4
Species	Homo sapiens (Human)
Gene	FFAR4
Synonym	PGR4 Omega-3 fatty acid receptor 1 O3FAR1 GT01 GPR129 GPR120 G-protein-coupled receptor GT01 G-protein coupled receptor PGR4 FFA4 receptor G-protein coupled receptor 129 G-protein coupled receptor 120 G protein-coupled receptor 129 G protein-coupled receptor 120 G-protein coupled receptor GT01 [ Show all ]
Disease	N/A
Length	377
Amino acid sequence	MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
UniProt	Q5NUL3
Protein Data Bank	N/A
GPCR-HGmod model	Q5NUL3
3D structure model	This predicted structure model is from GPCR-EXP Q5NUL3.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5339
IUPHAR	127
DrugBank	BE0003399

Ligand

Name	CHEMBL3311320
Molecular formula	C19H25NO2S
IUPAC name	4-tert-butyl-N-(2,4,6-trimethylphenyl)benzenesulfonamide
Molecular weight	331.474
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.2
Synonyms	MolPort-002-347-623 AN-652/10768041 Oprea1_834286 4-tert-butyl-N-(2,4,6-trimethylphenyl)benzenesulfonamide AC1LHBKK N-Mesityl-4-tert-butylbenzenesulfonamide BDBM50044916 ZINC361863 4-tert-butyl-N-mesitylbenzenesulfonamide MCULE-8856854691 AKOS001119535 Oprea1_519894 [ Show all ]
Inchi Key	FFIUKRRUBSQJBQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H25NO2S/c1-13-11-14(2)18(15(3)12-13)20-23(21,22)17-9-7-16(8-10-17)19(4,5)6/h7-12,20H,1-6H3
PubChem CID	835355
ChEMBL	CHEMBL3311320
IUPHAR	N/A
BindingDB	50044916
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<31622.8 nM	PMID24881566	ChEMBL
EC50	>31623.0 nM	PMID24881566	BindingDB

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