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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 6
Species	Homo sapiens (Human)
Gene	CCR6
Synonym	DRY6 G-protein coupled receptor 29 GPR-CY4 GPR29 GPRCY4 LARC receptor DRY-6 DCCR2 CKR-L3 Chemokine receptor-like 3 CD196 CCR6 CCR-6 CC-CKR-6 C-C CKR-6 STRL22 [ Show all ]
Disease	N/A
Length	374
Amino acid sequence	MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
UniProt	P51684
Protein Data Bank	N/A
GPCR-HGmod model	P51684
3D structure model	This predicted structure model is from GPCR-EXP P51684.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4423
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3187346
Molecular formula	C27H35N3O5
IUPAC name	3,4,5-trimethoxy-N-[9-[2-(4-methylanilino)-2-oxoethyl]-9-azabicyclo[3.3.1]nonan-3-yl]benzamide
Molecular weight	481.593
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.0
Synonyms	MLS-0472136.0001
Inchi Key	BZSNUGWDIOXXKE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H35N3O5/c1-17-8-10-19(11-9-17)28-25(31)16-30-21-6-5-7-22(30)15-20(14-21)29-27(32)18-12-23(33-2)26(35-4)24(13-18)34-3/h8-13,20-22H,5-7,14-16H2,1-4H3,(H,28,31)(H,29,32)
PubChem CID	60202246
ChEMBL	CHEMBL3187346
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<79000.0 nM	PubChem BioAssay data set	ChEMBL

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