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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Formyl peptide receptor-related sequence 1
Species	Mus musculus (Mouse)
Gene	Fpr-s1
Synonym	FPRL2 Lipoxin A4 receptor LXA4 receptor LXA4-R Lxa4r N-formyl peptide receptor 2 Fprl1 FPRH1 FPR3 Formyl peptide receptor-like 1 Formyl peptide receptor related sequence 1 FMLPY FMLP-related receptor I FMLP-R-I N-formyl peptide receptor 3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	351
Amino acid sequence	METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIALDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSFVSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPFRVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPILYVFMGQDFQERLIHSLSSRLQRALSEDSGHISDTRTNLASLPEDIEIKAI
UniProt	O08790
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3407315
IUPHAR	224
DrugBank	N/A

Ligand

Name	CHEMBL3590070
Molecular formula	C32H36N4O3
IUPAC name	(2R)-3-(1H-indol-3-yl)-2-[(4-methoxyphenyl)carbamoylamino]-N-[(1-phenylcyclohexyl)methyl]propanamide
Molecular weight	524.665
Hydrogen bond acceptor	3
Hydrogen bond donor	4
XlogP	6.2
Synonyms	(2R)-N-[(1-Phenylcyclohexyl)methyl]-3-(1H-indole-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamide BDBM50097562
Inchi Key	NMWHWNGAWSDIFW-GDLZYMKVSA-N
Inchi ID	InChI=1S/C32H36N4O3/c1-39-26-16-14-25(15-17-26)35-31(38)36-29(20-23-21-33-28-13-7-6-12-27(23)28)30(37)34-22-32(18-8-3-9-19-32)24-10-4-2-5-11-24/h2,4-7,10-17,21,29,33H,3,8-9,18-20,22H2,1H3,(H,34,37)(H2,35,36,38)/t29-/m1/s1
PubChem CID	122181319
ChEMBL	CHEMBL3590070
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	3800.0 nM	PMID25549897	ChEMBL
Efficacy	35.0 %	PMID25549897	ChEMBL

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