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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 3
Species	Mus musculus (Mouse)
Gene	Taar3
Synonym	G protein-coupled receptor 57 GPR57 mTaar3 TAAR3 TaR-3 trace amine associated receptor 3 (gene/pseudogene) trace amine receptor 3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	343
Amino acid sequence	MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRMIMYLFMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCDPLHYTTTMTVSMIKRLLAFCWAAPALFSFGLVLSEANVSGMQSYEILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALSDMPANTKGAVGKNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALQFIVSGKIFRSNSDTANLFPEAH
UniProt	Q5QD16
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	168
DrugBank	N/A

Ligand

Name	ISOAMYLAMINE
Molecular formula	C5H13N
IUPAC name	3-methylbutan-1-amine
Molecular weight	87.166
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	1.0
Synonyms	EINECS 203-526-0 I14-17836 ISOAMYLAMINE, REAG Isovalerylamine MFCD00008203 1-Butanamine, 3-methyl- RTR-001873 3-Methyl-1-butanamine # 3-methylbutyl amine ACMC-1C2LR C02640 CTK0H8363 FEMA No. 3219 iso-pentylamine Isopentylamine laquo gammaRaquo -isoamylamine (3-methyl-but-1-yl)-amine Monoisopentylamine 2-(2-isopropyl)ethylamine TRA0089077 3-Methyl-Butan-1-Amine amino 3-methylbutane DTXSID7059355 GTPL5506 Isopentylamine, analytical standard LPO0L33SHY 1-Amino-3-methylbutane NSC7907 3-methyl butylamine 3-METHYLBUTAN-1-AMINE AC1Q1PDF BMFVGAAISNGQNM-UHFFFAOYSA-N CHEBI:43689 F2190-0364 InChI=1/C5H13N/c1-5(2)3-4-6/h5H,3-4,6H2,1-2H Isobutylcarbylamine J-002023 MolPort-001-791-387 107-85-7 STL185592 3-Methyl-1-butanamine, 9CI 3-Methylbutylamine AI3-24040 D0XO7J FT-0616144 isoamyl amine Isopentylamine, 99% LEN (3-methylbutyl)amine NSC 7907 3,3-dimethyl-propylamine UNII-LPO0L33SHY 3-methyl-butyl-amine 7347AF ANW-15857 EC 203-526-0 I0082 Isoamylamine, 99% Isopentylamine, purum, >=98.0% (GC) MCULE-3081003576 1-Aminoisopentane Propylamine, 3,3-dimethyl- 3-Methyl-1-butanamine 3-Methylbutanamine AC1Q5499 Butylamine, 3-methyl- CHEMBL42003 FEMA 3219 iso-amyl amine isopentyl amine KS-00000UUZ Monoisoamylamine 11149-EP2316828A1 TR-001873 3-Methyl-1-butylamine 541-23-1 (hydrochloride) AKOS000119764 DB-040790 gamma-Isoamylamine isoamylamin Isopentylamine, >=98% Leucamine .gamma.-Isoamylamine NSC-7907 3,3-Dimethylpropylamine ZINC4658584 3-Methyl-Butylamine AC1L1PSO BDBM50024589 [ Show all ]
Inchi Key	BMFVGAAISNGQNM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C5H13N/c1-5(2)3-4-6/h5H,3-4,6H2,1-2H3
PubChem CID	7894
ChEMBL	N/A
IUPHAR	5506
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	10000.0 nM	PMID16878137	IUPHAR

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