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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	fMet-Leu-Phe receptor
Species	Homo sapiens (Human)
Gene	FPR1
Synonym	NFPR N-formylpeptide chemoattractant receptor N-formyl peptide receptor FPR1 FPR formyl peptide receptor 1 fMLP receptor fMLF-R [ Show all ]
Disease	Inflammatory disease Peptic ulcer
Length	350
Amino acid sequence	METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
UniProt	P21462
Protein Data Bank	N/A
GPCR-HGmod model	P21462
3D structure model	This predicted structure model is from GPCR-EXP P21462.
BioLiP	N/A
Therapeutic Target Database	T87831
ChEMBL	CHEMBL3359
IUPHAR	222
DrugBank	BE0000995

Ligand

Name	MLS000046638
Molecular formula	C21H32N2O3S
IUPAC name	(4-benzylpiperidin-1-yl)-(1-propylsulfonylpiperidin-3-yl)methanone
Molecular weight	392.558
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.1
Synonyms	REGID_for_CID_3237289 (4-benzylpiperidino)-(1-propylsulfonyl-3-piperidyl)methanone EU-0098038 [4-(phenylmethyl)piperidin-1-yl]-(1-propylsulfonylpiperidin-3-yl)methanone AC1MME1E CHEMBL1430943 SMR000032649 3-[(4-benzylpiperidin-1-yl)carbonyl]-1-(propylsulfonyl)piperidine HMS2157J07 BDBM37695 NCGC00050246-02 (4-benzylpiperidin-1-yl)-(1-propylsulfonylpiperidin-3-yl)methanone cid_3237289 [4-(phenylmethyl)-1-piperidinyl]-(1-propylsulfonyl-3-piperidinyl)methanone HMS3308J21 [ Show all ]
Inchi Key	ANDSXDKABIYGPB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H32N2O3S/c1-2-15-27(25,26)23-12-6-9-20(17-23)21(24)22-13-10-19(11-14-22)16-18-7-4-3-5-8-18/h3-5,7-8,19-20H,2,6,9-17H2,1H3
PubChem CID	3237289
ChEMBL	CHEMBL1430943
IUPHAR	N/A
BindingDB	37695
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<66700.0 nM	N/A	BindingDB
Ki	<43700.0 nM	N/A	BindingDB
Ki	<66700.0 nM	PubChem BioAssay data set	ChEMBL

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