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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS003178969
Molecular formula	C34H33FN2O5S2
IUPAC name	(2S,4aR,7S,8aS)-2-(2-fluorophenyl)-1,6-bis-(4-methylphenyl)sulfonyl-7-phenyl-3,4a,5,7,8,8a-hexahydro-2H-1,6-naphthyridin-4-one
Molecular weight	632.765
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	5.5
Synonyms	CHEMBL2138232 SMR001882763
Inchi Key	ACNCSONPLWHQFX-PESDVKBKSA-N
Inchi ID	InChI=1S/C34H33FN2O5S2/c1-23-12-16-26(17-13-23)43(39,40)36-22-29-32(20-31(36)25-8-4-3-5-9-25)37(44(41,42)27-18-14-24(2)15-19-27)33(21-34(29)38)28-10-6-7-11-30(28)35/h3-19,29,31-33H,20-22H2,1-2H3/t29-,31+,32+,33+/m1/s1
PubChem CID	51359282
ChEMBL	CHEMBL2138232
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1709	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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