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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TANDOSPIRONE HYDROCHLORIDE
Molecular formula	C21H30ClN5O2
IUPAC name	(1R,2S,6R,7S)-4-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione;hydrochloride
Molecular weight	419.954
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	None
Synonyms	Metanopirone 99095-10-0 SCHEMBL1766255 CHEMBL1628275 Tandospirone hydrochloride [MI] (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride MolPort-023-276-589 AKOS024457315 Sediel DTXSID30243943 UNII-RWR6SLB9P6 4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, hydrochloride (1:1), (3aR,4S,7R,7aS)-rel- RWR6SLB9P6 [ Show all ]
Inchi Key	ACVFJYKNBOHIMH-DPFKZJTMSA-N
Inchi ID	InChI=1S/C21H29N5O2.ClH/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21;/h3,6-7,15-18H,1-2,4-5,8-14H2;1H/t15-,16+,17+,18-;
PubChem CID	13422623
ChEMBL	CHEMBL1628275
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1966	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
1967	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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