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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000678714
Molecular formula	C17H18BrNO4
IUPAC name	(5-bromofuran-2-yl)-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)methanone
Molecular weight	380.238
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.7
Synonyms	(5-bromo-2-furanyl)-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)methanone Oprea1_632419 (5-bromofuran-2-yl)-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)methanone HMS2550C03 SR-01000479023-1 AKOS005450797 MolPort-002-087-440 (5-bromo-2-furyl)-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)methanone CHEMBL1431893 SMR000269781 2-(5-bromo-2-furoyl)-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline MCULE-7500372084 STK381606 (5-bromanylfuran-2-yl)-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)methanone BDBM69025 Oprea1_259389 (5-bromofuran-2-yl)(6,7-dimethoxy-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone cid_2905396 SR-01000479023 AC1MELTJ [ Show all ]
Inchi Key	ADNJEBVHGYYVSD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18BrNO4/c1-10-12-9-15(22-3)14(21-2)8-11(12)6-7-19(10)17(20)13-4-5-16(18)23-13/h4-5,8-10H,6-7H2,1-3H3
PubChem CID	2905396
ChEMBL	CHEMBL1431893
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463220	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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