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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1LQJ8G
Molecular formula	C19H22F3N5O2S
IUPAC name	4-[4-(2,5-dimethylphenyl)piperazin-1-yl]-4-oxo-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]butanamide
Molecular weight	441.473
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	2.5
Synonyms	AKOS005696437 MolPort-002-608-910 CHEMBL1548857 ZINC9193118 714942-72-0 MLS001142499 AKOS032387304 SMR000648047 4-[4-(2,5-dimethylphenyl)piperazin-1-yl]-4-oxo-N-[(2Z)-5-(trifluoromethyl)-1,3,4-thiadiazol-2(3H)-ylidene]butanamide HMS2934M10 MolPort-000-775-775 STL042937 4-[4-(2,5-dimethylphenyl)piperazin-1-yl]-4-oxo-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]butanamide MCULE-4933678433 [ Show all ]
Inchi Key	ADQUXCDSEMBIKZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22F3N5O2S/c1-12-3-4-13(2)14(11-12)26-7-9-27(10-8-26)16(29)6-5-15(28)23-18-25-24-17(30-18)19(20,21)22/h3-4,11H,5-10H2,1-2H3,(H,23,25,28)
PubChem CID	1401684
ChEMBL	CHEMBL1548857
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2987	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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