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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1LCK6H
Molecular formula	C23H28N2O5
IUPAC name	N-[2-(cyclopentylamino)-1-(2,3-dimethoxyphenyl)-2-oxoethyl]-N-cyclopropylfuran-2-carboxamide
Molecular weight	412.486
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.6
Synonyms	Furan-2-carboxylic acid [cyclopentylcarbamoyl-(2,3-dimethoxy-phenyl)-methyl]-cyclopropyl-amide N-[2-(cyclopentylamino)-1-(2,3-dimethoxyphenyl)-2-oxoethyl]-N-cyclopropylfuran-2-carboxamide SMR000004261 HMS2176J14 AKOS000700538 Oprea1_203802 CHEMBL1299612 MLS000032407 Oprea1_845340 ASN 05256714 [ Show all ]
Inchi Key	AEGOBAOSTAGKEJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28N2O5/c1-28-18-10-5-9-17(21(18)29-2)20(22(26)24-15-7-3-4-8-15)25(16-12-13-16)23(27)19-11-6-14-30-19/h5-6,9-11,14-16,20H,3-4,7-8,12-13H2,1-2H3,(H,24,26)
PubChem CID	651508
ChEMBL	CHEMBL1299612
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3450	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463304	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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