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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1395392
Molecular formula	C22H24FN3O5S2
IUPAC name	1-[4-(4,7-dimethoxy-1,3-benzothiazol-2-yl)piperazin-1-yl]-3-(4-fluorophenyl)sulfonylpropan-1-one
Molecular weight	493.568
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	3.0
Synonyms	2-(4-{3-[(4-fluorophenyl)sulfonyl]propanoyl}piperazin-1-yl)-4,7-dimethoxy-1,3-benzothiazole MCULE-3419358526 ZINC8601670 G856-9170 897486-38-3 MolPort-003-142-573 1-(4-(4,7-dimethoxybenzo[d]thiazol-2-yl)piperazin-1-yl)-3-((4-fluorophenyl)sulfonyl)propan-1-one HMS1905N03 AKOS002061630 NCGC00136852-01 F2609-2783 [ Show all ]
Inchi Key	AEMCUKKSEGNPHS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24FN3O5S2/c1-30-17-7-8-18(31-2)21-20(17)24-22(32-21)26-12-10-25(11-13-26)19(27)9-14-33(28,29)16-5-3-15(23)4-6-16/h3-8H,9-14H2,1-2H3
PubChem CID	16032675
ChEMBL	CHEMBL1395392
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3626	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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