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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000058033
Molecular formula	C22H24N2O3
IUPAC name	N-(2-methoxyphenyl)-2-methyl-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]propanamide
Molecular weight	364.445
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.6
Synonyms	AC1LD6TE MLS000040030 NCGC00019167-02 MolPort-002-596-210 ZINC8855118 HMS3319J02 N-(2-methoxyphenyl)-2-methyl-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]propanamide AKOS003649258 MLS002582513 CHEMBL1454494 N-((2-hydroxy-8-methylquinolin-3-yl)methyl)-N-(2-methoxyphenyl)isobutyramide 674817-03-9 MCULE-4847991572 NCGC00019167-01 AKOS005488625 MolPort-000-752-719 STK563081 HMS2172E08 N-(2-methoxyphenyl)-2-methyl-N-[(8-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]propanamide [ Show all ]
Inchi Key	AETXHFAHKNQZKZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24N2O3/c1-14(2)22(26)24(18-10-5-6-11-19(18)27-4)13-17-12-16-9-7-8-15(3)20(16)23-21(17)25/h5-12,14H,13H2,1-4H3,(H,23,25)
PubChem CID	662158
ChEMBL	CHEMBL1454494
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463347	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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