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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000149143
Molecular formula	C19H24N4O3
IUPAC name	8-methoxy-5-methyl-3-(3-morpholin-4-ylpropyl)pyrimido[5,4-b]indol-4-one
Molecular weight	356.426
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	1.3
Synonyms	AC1LXTYI MLS000558827 8-methoxy-5-methyl-3-(3-morpholin-4-ylpropyl)pyrimido[5,4-b]indol-4-one STK583196 8-methoxy-5-methyl-3-[3-(morpholin-4-yl)propyl]-3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one HMS2464A17 AKOS005506494 MolPort-002-641-045 8-methoxy-5-methyl-3-(3-morpholinopropyl)pyrimid[5,4-b]indol-4-one CHEMBL1299871 ZINC20518427 896840-31-6 MCULE-4820435100 8-Methoxy-5-methyl-3-(3-morpholin-4-yl-propyl)-3,5-dihydro-pyrimido[5,4-b]indol-4-one BDBM51663 8-methoxy-5-methyl-3-[3-(4-morpholinyl)propyl]-4-pyrimido[5,4-b]indolone cid_1858288 [ Show all ]
Inchi Key	AFIQKGQJDGBSIA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H24N4O3/c1-21-16-5-4-14(25-2)12-15(16)17-18(21)19(24)23(13-20-17)7-3-6-22-8-10-26-11-9-22/h4-5,12-13H,3,6-11H2,1-2H3
PubChem CID	1858288
ChEMBL	CHEMBL1299871
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4184	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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