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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001090541
Molecular formula	C25H31N5O
IUPAC name	(5-methylimidazo[1,2-a]pyridin-2-yl)-[3-[4-(2-methylphenyl)piperazin-1-yl]piperidin-1-yl]methanone
Molecular weight	417.557
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.5
Synonyms	(5-methylimidazo[1,2-a]pyridin-2-yl)-[3-[4-(o-tolyl)piperazino]piperidino]methanone (5-methyl-2-imidazo[1,2-a]pyridinyl)-[3-[4-(2-methylphenyl)-1-piperazinyl]-1-piperidinyl]methanone HMS2955C12 5-methyl-2-({3-[4-(2-methylphenyl)-1-piperazinyl]-1-piperidinyl}carbonyl)imidazo[1,2-a]pyridine MolPort-004-998-034 CHEMBL1717568 (5-methylimidazo[1,2-a]pyridin-2-yl)-[3-[4-(2-methylphenyl)piperazin-1-yl]piperidin-1-yl]methanone MCULE-3048817902 BDBM91080 SMR000653606 cid_24817180 [ Show all ]
Inchi Key	AFXPSVBKEDKEMP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31N5O/c1-19-7-3-4-10-23(19)28-15-13-27(14-16-28)21-9-6-12-29(17-21)25(31)22-18-30-20(2)8-5-11-24(30)26-22/h3-5,7-8,10-11,18,21H,6,9,12-17H2,1-2H3
PubChem CID	24817180
ChEMBL	CHEMBL1717568
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4595	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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