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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL376456
Molecular formula	C12H14N2O2
IUPAC name	7-methoxy-2,3,4,10b-tetrahydro-1H-pyrazino[1,2-b]isoindol-6-one
Molecular weight	218.256
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	0.3
Synonyms	SCHEMBL3557954 (+/-)-1,3,4,10b-tetrahydro-7-methoxy-pyrazino[2,1-a]isoindol-6(2H)-one AGESLMCHEVXSAE-UHFFFAOYSA-N (+/-)-7-methoxy-1,3,4,10b-tetrahydropyrazino[2,1-a]isoindol-6(2H)-one BDBM50205897
Inchi Key	AGESLMCHEVXSAE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H14N2O2/c1-16-10-4-2-3-8-9-7-13-5-6-14(9)12(15)11(8)10/h2-4,9,13H,5-7H2,1H3
PubChem CID	11290492
ChEMBL	CHEMBL376456
IUPHAR	N/A
BindingDB	50205897
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4810	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
4811	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
4809	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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