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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1OFNKC
Molecular formula	C14H14N4OS
IUPAC name	6-[(2,5-dimethylphenyl)methylsulfanyl]-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one
Molecular weight	286.353
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.5
Synonyms	CHEMBL1497681 SR-01000019932-1 6-[(2,5-dimethylphenyl)methylsulfanyl]-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one MCULE-6956146513 AKOS024653465 SMR000324919 F2503-0097 ZINC13543815 877630-39-2 MLS000684976 SR-01000019932 6-((2,5-dimethylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one HMS2620M21 MolPort-003-126-056 [ Show all ]
Inchi Key	AGHQGVCMUKWYEM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H14N4OS/c1-8-3-4-9(2)10(5-8)7-20-14-16-12-11(6-15-18-12)13(19)17-14/h3-6H,7H2,1-2H3,(H2,15,16,17,18,19)
PubChem CID	135472825
ChEMBL	CHEMBL1497681
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4880	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463477	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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