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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL377270
Molecular formula	C31H28F4N4O
IUPAC name	3-[4-[[1-(cyclopropylmethyl)piperidin-4-ylidene]-[5-fluoro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]methyl]phenyl]benzamide
Molecular weight	548.586
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	6.2
Synonyms	4''-[(1-cyclopropylmethyl-piperidin-4-ylidene)-(5-fluoro-6-trifluoromethyl-1H-benzoimidazol-2-yl)-methyl]-biphenyl-3-carboxylic acid amide BDBM50186836
Inchi Key	AGMAFERLZIQTJG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H28F4N4O/c32-25-16-27-26(15-24(25)31(33,34)35)37-30(38-27)28(21-10-12-39(13-11-21)17-18-4-5-18)20-8-6-19(7-9-20)22-2-1-3-23(14-22)29(36)40/h1-3,6-9,14-16,18H,4-5,10-13,17H2,(H2,36,40)(H,37,38)
PubChem CID	44413271
ChEMBL	CHEMBL377270
IUPHAR	N/A
BindingDB	50186836
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5009	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
5010	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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