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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-methyl-4-(2-oxo-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethoxy)quinolin-2(1H)-one
Molecular formula	C23H22F3N3O3
IUPAC name	1-methyl-4-[2-oxo-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethoxy]quinolin-2-one
Molecular weight	445.442
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.2
Synonyms	HMS2395P05 ZINC4056984 1-methyl-4-[2-oxo-2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethoxy]quinolin-2-one MLS002587395 SR-01000621197 MCULE-1792177917 AC1MMM4L MolPort-007-641-696 CHEMBL1424768 SR-01000621197-2 MLS000089520 AKOS001838719 SMR000027868 [ Show all ]
Inchi Key	AGXBIAZNJSPVBG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22F3N3O3/c1-27-19-8-3-2-7-18(19)20(14-21(27)30)32-15-22(31)29-11-9-28(10-12-29)17-6-4-5-16(13-17)23(24,25)26/h2-8,13-14H,9-12,15H2,1H3
PubChem CID	3240891
ChEMBL	CHEMBL1424768
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5312	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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