Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	6088-51-3
Molecular formula	C20H14O2S2
IUPAC name	6-[(6-hydroxynaphthalen-2-yl)disulfanyl]naphthalen-2-ol
Molecular weight	350.45
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	5.8
Synonyms	NCGC00091570-03 SBB005947 Y4YW3C2D2S 2-Naphthalenol, 6,6'-dithiobis- 6,6'-Disulfanediylbis(naphthalen-2-ol) 6-Hydroxy-2-naphthyldisulfide AC1L2KFB C-20629 DDD (6-hydroxy-2-naphthyl disulfide) FT-0635967 LS-266 NCIOpen2_009428 Tox21_200789 2,2'-DIHYDROXY-6,6'-DINAPHTHYL DISULFIDE, 2-Naphthol, 6,6'-dithiodi- 6,6'-dithiodi(2-naphthol) 6-[(6-hydroxynaphthalen-2-yl)disulfanyl]naphthalen-2-ol AI3-61075 DSSTox_CID_5429 NCGC00091570-01 NSC87629 UNII-Y4YW3C2D2S 2,6'-dinaphthyl disulfide 6,6 inverted exclamation marka-Dithiodi(2-naphthol) 6-(6-hydroxynaphthalen-2-yl)disulfanylnaphthalen-2-ol 6545AF B5541 CTK8B2012 DTXSID7025429 NCGC00257271-01 SCHEMBL146470 ZINC1562198 2-Naphthalenol,6'-dithiobis- 6,6'-disulfanediyldinaphthalen-2-ol 6-[(6-hydroxy-2-naphthalenyl)disulfanyl]-2-naphthalenol ACMC-209mmz CAS-6088-51-3 DDD (analytical) I14-51223 MCULE-2620524693 NSC 87629 Tox21_303354 2,2'-Dihydroxy-6,6'-dinaphthyldisulfide 2-Naphthol, 6,6'-dithiodi- (8CI) 6,6'-Dithiodi-2-naphthol 6-[(6-oxidanylnaphthalen-2-yl)disulfanyl]naphthalen-2-ol AKOS000267803 CHEMBL1489064 DSSTox_GSID_25429 NCGC00091570-02 PIR 3.5 VZ21967 2,6'-naphthyl disulfide 6,6'-Dihydroxy-2,2'-dinaphthyl disulfide 6-Hydroxy-2-naphthyl disulfide A832938 Bis(6-hydroxy-2-naphthyl) disulfide D0244 EINECS 228-025-4 InChI=1/C20H14O2S2/c21-17-5-1-15-11-19(7-3-13(15)9-17)23-24-20-8-4-14-10-18(22)6-2-16(14)12-20/h1-12,21-22H NCGC00258343-01 ST056180 2,2'-Dihydroxy-6,6'-dinaphthyl disulfide 2-Naphthalenol,6,6'-dithiobis- 6,6'-Dithiobis-2-naphthalenol 6-[(6-hydroxy-2-naphthyl)disulfanyl]naphthalen-2-ol AHXGXXJEEHFHDK-UHFFFAOYSA- CCRIS 6047 DDD0 MolPort-000-478-291 NSC-87629 TR-020989 2,2'-Dihydroxy-6,6'-naphthyl disulfide 2-Naphthol,6'-dithiodi- 6,6'-Dithiodi-2-naphthtol ANW-33609 CJ-24578 DSSTox_RID_77783 [ Show all ]
Inchi Key	AHXGXXJEEHFHDK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H14O2S2/c21-17-5-1-15-11-19(7-3-13(15)9-17)23-24-20-8-4-14-10-18(22)6-2-16(14)12-20/h1-12,21-22H
PubChem CID	22463
ChEMBL	CHEMBL1489064
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5953	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218