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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL559013
Molecular formula	C21H21N5O
IUPAC name	2-[4-[2-(1H-indol-3-yl)acetyl]piperazin-1-yl]-2-pyridin-3-ylacetonitrile
Molecular weight	359.433
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.7
Synonyms	[4-(2-1H-Indol-3-yl-acetyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile; trihydrochloride; hydrate BDBM50003557 SCHEMBL9852863 2-[4-[(1H-Indol-3-yl)acetyl]-1-piperazinyl]-2-(3-pyridinyl)acetonitrile CHEMBL1197021
Inchi Key	AHYCZKBAGLLOFG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21N5O/c22-13-20(16-4-3-7-23-14-16)25-8-10-26(11-9-25)21(27)12-17-15-24-19-6-2-1-5-18(17)19/h1-7,14-15,20,24H,8-12H2
PubChem CID	10428543
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50003557
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
519724	Platelet-activating factor receptor	P21556	PTAFR	Cavia porcellus (Guinea pig)	342

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