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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	5-(4,5-dimethyl-3-thienyl)-4-(1-phenylethyl)-4H-1,2,4-triazole-3-thiol
Molecular formula	C16H17N3S2
IUPAC name	3-(4,5-dimethylthiophen-3-yl)-4-(1-phenylethyl)-1H-1,2,4-triazole-5-thione
Molecular weight	315.453
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.0
Synonyms	AK-968/41923209 MolPort-001-553-329 3-(4,5-dimethylthiophen-3-yl)-4-(1-phenylethyl)-1H-1,2,4-triazole-5-thione STK450001 5-(4,5-dimethylthiophen-3-yl)-4-(1-phenylethyl)-4H-1,2,4-triazole-3-thiol MCULE-5004718999 AKOS003289229 SMR000228111 5-(4,5-dimethyl(3-thienyl))-4-(phenylethyl)-1,2,4-triazole-3-thiol CHEMBL1445732 AC1N4IPQ MLS000698585 AKOS022148688 ST50832599 HMS2575M13 [ Show all ]
Inchi Key	AHYVDGFPKYGUAE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17N3S2/c1-10-12(3)21-9-14(10)15-17-18-16(20)19(15)11(2)13-7-5-4-6-8-13/h4-9,11H,1-3H3,(H,18,20)
PubChem CID	4129464
ChEMBL	CHEMBL1445732
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5997	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463602	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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