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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001225295
Molecular formula	C24H27N5O5S
IUPAC name	4-amino-5-N-[2-(cyclohexylamino)-1-(furan-2-yl)-2-oxoethyl]-5-N-(2-methoxyphenyl)-1,2-thiazole-3,5-dicarboxamide
Molecular weight	497.57
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	3.3
Synonyms	4-Amino-isothiazole-3,5-dicarboxylic acid 3-amide 5-[(cyclohexylcarbamoyl-furan-2-yl-methyl)-(2-methoxy-phenyl)-amide] ASN 03900257 SMR000599924 4-azanyl-N5-[2-(cyclohexylamino)-1-(furan-2-yl)-2-oxidanylidene-ethyl]-N5-(2-methoxyphenyl)-1,2-thiazole-3,5-dicarboxamide CHEMBL1388042 AKOS000797724 4-amino-N''-[2-(cyclohexylamino)-1-(2-furyl)-2-keto-ethyl]-N''-(2-methoxyphenyl)isothiazole-3,5-dicarboxamide BDBM62160 cid_3180687 4-amino-5-N-[2-(cyclohexylamino)-1-(furan-2-yl)-2-oxoethyl]-5-N-(2-methoxyphenyl)-1,2-thiazole-3,5-dicarboxamide AKOS024308902 Oprea1_462217 4-amino-N5-[2-(cyclohexylamino)-1-(2-furanyl)-2-oxoethyl]-N5-(2-methoxyphenyl)isothiazole-3,5-dicarboxamide AC1MKKPJ MCULE-6523869858 [ Show all ]
Inchi Key	AJIYPQQWLOFUGX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27N5O5S/c1-33-16-11-6-5-10-15(16)29(24(32)21-18(25)19(22(26)30)28-35-21)20(17-12-7-13-34-17)23(31)27-14-8-3-2-4-9-14/h5-7,10-14,20H,2-4,8-9,25H2,1H3,(H2,26,30)(H,27,31)
PubChem CID	3180687
ChEMBL	CHEMBL1388042
IUPHAR	N/A
BindingDB	62160
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6956	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
6957	Neuropeptides B/W receptor type 1	P48145	NPBWR1	Homo sapiens (Human)	328
463742	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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