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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL233440
Molecular formula	C26H31N3O4
IUPAC name	3-hydroxy-2-[4-methoxy-3-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]-4-methyl-3H-pyrrolo[3,4-b]indol-1-one
Molecular weight	449.551
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.3
Synonyms	N/A
Inchi Key	AKJANOFIDXVZOZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H31N3O4/c1-17-10-12-28(13-11-17)14-15-33-22-16-18(8-9-21(22)32-3)29-25(30)23-19-6-4-5-7-20(19)27(2)24(23)26(29)31/h4-9,16-17,26,31H,10-15H2,1-3H3
PubChem CID	44430566
ChEMBL	CHEMBL233440
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7597	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
7598	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
7596	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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