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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-874OEY3JEJ
Molecular formula	C22H26Cl2N4
IUPAC name	3-(2,4-dichlorophenyl)-9-heptan-4-yl-6-methyl-1,2,5,9-tetrazatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraene
Molecular weight	417.378
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	6.3
Synonyms	NBI-34041 BDBM50171325 SCHEMBL16606732 2-(2,4-Dichloro-phenyl)-4-methyl-6-(1-propyl-butyl)-7,8-dihydro-6H-1,3,6,8a-tetraaza-acenaphthylene KB-79290 6H-1,3,6,8a-Tetraazaacenaphthylene, 2-(2,4-dichlorophenyl)-7,8-dihydro-4-methyl-6-(1-propylbutyl)- SB-723620 268545-87-5 NBI 34041 874OEY3JEJ SB723620 1-(2,4-Dichlorophenyl)-5-(heptan-4-yl)-7-methyl-4,5-dihydro-3H-2,2a,5,8-tetraazaacenaphthylene CHEMBL188907 ZINC28465228 [ Show all ]
Inchi Key	AKLMUGFDGONMAA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26Cl2N4/c1-4-6-16(7-5-2)27-10-11-28-22-19(27)12-14(3)25-21(22)20(26-28)17-9-8-15(23)13-18(17)24/h8-9,12-13,16H,4-7,10-11H2,1-3H3
PubChem CID	9888194
ChEMBL	CHEMBL188907
IUPHAR	N/A
BindingDB	50171325
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7663	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444

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