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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL137208
Molecular formula	C25H24N4O2
IUPAC name	1-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)-3-[(1S)-1-phenylethyl]urea
Molecular weight	412.493
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.8
Synonyms	BDBM50043486 1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(1-phenyl-ethyl)-urea
Inchi Key	AMJHJWQKGLQESV-NVHKAFQKSA-N
Inchi ID	InChI=1S/C25H24N4O2/c1-17(18-11-5-3-6-12-18)26-25(31)28-23-24(30)29(2)21-16-10-9-15-20(21)22(27-23)19-13-7-4-8-14-19/h3-17,23H,1-2H3,(H2,26,28,31)/t17-,23?/m0/s1
PubChem CID	10364355
ChEMBL	CHEMBL137208
IUPHAR	N/A
BindingDB	50043486
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8943	Cholecystokinin receptor type A	P30551	Cckar	Rattus norvegicus (Rat)	444
8944	Gastrin/cholecystokinin type B receptor	P32239	CCKBR	Homo sapiens (Human)	447

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