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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3746079
Molecular formula	C24H33FN2O3S
IUPAC name	N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-4-fluoro-N-methylbenzenesulfonamide
Molecular weight	448.597
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.1
Synonyms	BDBM50134693
Inchi Key	APKDIQSHDGVEMU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H33FN2O3S/c1-24(2,3)22-7-5-6-8-23(22)30-18-17-27-15-13-20(14-16-27)26(4)31(28,29)21-11-9-19(25)10-12-21/h5-12,20H,13-18H2,1-4H3
PubChem CID	127041563
ChEMBL	CHEMBL3746079
IUPHAR	N/A
BindingDB	50134693
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521753	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
521754	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
521751	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
521752	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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