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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000735366
Molecular formula	C21H28N2O3S
IUPAC name	ethyl 1-[(2-methyl-1,3-thiazol-5-yl)methyl]-4-(2-phenoxyethyl)piperidine-4-carboxylate
Molecular weight	388.526
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.8
Synonyms	1-[(2-methyl-5-thiazolyl)methyl]-4-(2-phenoxyethyl)-4-piperidinecarboxylic acid ethyl ester ethyl 1-[(2-methyl-1,3-thiazol-5-yl)methyl]-4-(2-phenoxyethyl)piperidine-4-carboxylate ZINC13595824 BDBM83332 cid_16187535 SR-01000176827 1-[(2-methylthiazol-5-yl)methyl]-4-(2-phenoxyethyl)isonipecotic acid ethyl ester HMS2675D15 MolPort-005-118-245 ethyl 1-[(2-methyl-1,3-thiazol-5-yl)methyl]-4-(2-phenoxyethyl)-4-piperidinecarboxylate SR-01000176827-1 MCULE-8385958346 CHEMBL1345157 SMR000319337 [ Show all ]
Inchi Key	AQDWISRSCBMKHV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H28N2O3S/c1-3-25-20(24)21(11-14-26-18-7-5-4-6-8-18)9-12-23(13-10-21)16-19-15-22-17(2)27-19/h4-8,15H,3,9-14,16H2,1-2H3
PubChem CID	16187535
ChEMBL	CHEMBL1345157
IUPHAR	N/A
BindingDB	83332
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11605	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
11604	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
11603	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
11602	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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