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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL42231
Molecular formula	C27H31NO3
IUPAC name	2-(2,6-dimethoxyphenoxy)-N-[(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)methyl]ethanamine
Molecular weight	417.549
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.5
Synonyms	BDBM50409688
Inchi Key	BJGAWQMDTQOSCU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31NO3/c1-29-25-13-8-14-26(30-2)27(25)31-16-15-28-19-20-17-22-11-6-7-12-23(22)24(18-20)21-9-4-3-5-10-21/h3-14,20,24,28H,15-19H2,1-2H3
PubChem CID	44289261
ChEMBL	CHEMBL42231
IUPHAR	N/A
BindingDB	50409688
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25054	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
25050	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
25051	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
25048	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
25053	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
25049	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
25052	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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