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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3663499
Molecular formula	C23H22N8O
IUPAC name	[6-methyl-3-(triazol-2-yl)pyridin-2-yl]-[2-(quinoxalin-2-ylamino)-7-azabicyclo[2.2.1]heptan-7-yl]methanone
Molecular weight	426.484
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.1
Synonyms	US9062078, 230 BDBM164100 SCHEMBL16041110 US9062078, 205 BDBM164075
Inchi Key	CSASZLQIJMDWMO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22N8O/c1-14-6-8-20(31-25-10-11-26-31)22(27-14)23(32)30-15-7-9-19(30)18(12-15)29-21-13-24-16-4-2-3-5-17(16)28-21/h2-6,8,10-11,13,15,18-19H,7,9,12H2,1H3,(H,28,29)
PubChem CID	90412570
ChEMBL	CHEMBL3663499
IUPHAR	N/A
BindingDB	164075, 164100
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
468967	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
517565	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
468966	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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