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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL121943
Molecular formula	C22H22F3N5O3
IUPAC name	[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-[2-(trifluoromethyl)phenyl]methanone
Molecular weight	461.445
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	3.5
Synonyms	N/A
Inchi Key	CTKIHMWDMFAPKL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22F3N5O3/c1-32-17-11-14-16(12-18(17)33-2)27-21(28-19(14)26)30-9-7-29(8-10-30)20(31)13-5-3-4-6-15(13)22(23,24)25/h3-6,11-12H,7-10H2,1-2H3,(H2,26,27,28)
PubChem CID	10647689
ChEMBL	CHEMBL121943
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
50173	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
50172	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
50174	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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