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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL584545
Molecular formula	C32H38N4O4
IUPAC name	2-[4-amino-1-(3,4-dimethoxyphenyl)butyl]-4-[4-[(1R)-1-phenylethyl]piperazin-1-yl]isoindole-1,3-dione
Molecular weight	542.68
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.0
Synonyms	2-[4-amino-1-(3,4-dimethoxy-phenyl)-butyl]-4-[4-(1R)-(1-phenyl-ethyl)-piperazin-1-yl]-isoindole-1,3-dione SCHEMBL1472736 2-(4-amino-1-(3,4-dimethoxyphenyl)butyl)-4-(4-((R)-1-phenylethyl)piperazin-1-yl)isoindoline-1,3-dione BDBM50302239 DCILHRAUYUGNNL-FPSALIRRSA-N
Inchi Key	DCILHRAUYUGNNL-FPSALIRRSA-N
Inchi ID	InChI=1S/C32H38N4O4/c1-22(23-9-5-4-6-10-23)34-17-19-35(20-18-34)27-12-7-11-25-30(27)32(38)36(31(25)37)26(13-8-16-33)24-14-15-28(39-2)29(21-24)40-3/h4-7,9-12,14-15,21-22,26H,8,13,16-20,33H2,1-3H3/t22-,26?/m1/s1
PubChem CID	23627251
ChEMBL	CHEMBL584545
IUPHAR	N/A
BindingDB	50302239
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
56384	Urotensin-2 receptor	Q9UKP6	UTS2R	Homo sapiens (Human)	389
56385	Urotensin-2 receptor	P49684	Uts2r	Rattus norvegicus (Rat)	386

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