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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL471060
Molecular formula	C27H33N3O4S
IUPAC name	4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-N-methylsulfonyl-2-(propan-2-ylamino)benzamide
Molecular weight	495.638
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	4.4
Synonyms	BDBM50277529 SCHEMBL4584945 4''-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-3-(isopropylamino)-N-(methylsulfonyl)biphenyl-4-carboxamide Dihydrochloride CHEMBL1186589
Inchi Key	FEQQLEGJQNYEQY-SANMLTNESA-N
Inchi ID	InChI=1S/C27H33N3O4S/c1-19(2)29-25-17-23(13-14-24(25)27(32)30-35(3,33)34)21-11-9-20(10-12-21)15-16-28-18-26(31)22-7-5-4-6-8-22/h4-14,17,19,26,28-29,31H,15-16,18H2,1-3H3,(H,30,32)/t26-/m0/s1
PubChem CID	11420551
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50277529
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
76538	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
459921	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
76536	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
76537	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405

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