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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3954140
Molecular formula	C18H23F3N2O2
IUPAC name	2-[3-[4-(trifluoromethyl)pyridin-2-yl]-3-azaspiro[5.5]undecan-9-yl]acetic acid
Molecular weight	356.389
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.5
Synonyms	BDBM50208108 SCHEMBL16482947
Inchi Key	GCHINJJAFUYXMP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H23F3N2O2/c19-18(20,21)14-3-8-22-15(12-14)23-9-6-17(7-10-23)4-1-13(2-5-17)11-16(24)25/h3,8,12-13H,1-2,4-7,9-11H2,(H,24,25)
PubChem CID	73777174
ChEMBL	CHEMBL3954140
IUPHAR	N/A
BindingDB	50208108
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
538302	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300
538300	Free fatty acid receptor 4	Q7TMA4	Ffar4	Mus musculus (Mouse)	361
538301	Free fatty acid receptor 4	Q5NUL3	FFAR4	Homo sapiens (Human)	377

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