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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000176604
Molecular formula	C28H29NO
IUPAC name	1,3,5-trimethyl-2,6-diphenyl-4-(2-phenylethynyl)piperidin-4-ol
Molecular weight	395.546
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.7
Synonyms	1,3,5-trimethyl-2,6-diphenyl-4-(2-phenylethynyl)piperidin-4-ol BDBM79997 Oprea1_231651 499191-71-8 cid_3127163 AKOS005221763 MLS000566842 1,3,5-trimethyl-2,6-diphenyl-4-(phenylethynyl)piperidin-4-ol Oprea1_504407 HMS2538I05 ST059936 1,3,5-trimethyl-2,6-diphenyl-4-(2-phenylethynyl)-4-piperidinol BAS 01176298 MolPort-001-957-299 1,3,5-Trimethyl-2,6-diphenyl-4-phenylethynyl-piperidin-4-ol CHEMBL1351473 REGID_for_CID_3127163 AC1MIVGE MCULE-1431885681 STL297539 [ Show all ]
Inchi Key	HMVLFUWQWMPWKQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H29NO/c1-21-26(24-15-9-5-10-16-24)29(3)27(25-17-11-6-12-18-25)22(2)28(21,30)20-19-23-13-7-4-8-14-23/h4-18,21-22,26-27,30H,1-3H3
PubChem CID	3127163
ChEMBL	CHEMBL1351473
IUPHAR	N/A
BindingDB	79997
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
118993	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
118994	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
477564	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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