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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Conivaptan
Molecular formula	C32H26N4O2
IUPAC name	N-[4-(2-methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamide
Molecular weight	498.586
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.7
Synonyms	BCP07817 Conivaptan [INN] I14-8805 N-[4-({4-methyl-3,5,9-triazatricyclo[8.4.0.0;{2,6}]tetradeca-1(10),2(6),3,11,13-pentaen-9-yl}carbonyl)phenyl]-2-phenylbenzamide UNII-0NJ98Y462X 4'-[(2-Methyl-1,4,5,6-tetrahydroimidazo[4,5-d][1]benzazepin-6-yl)carbonyl]-2-phenylbenzanilide CHEBI:681850 L001531 NCGC00345881-05 YM-087 (1,1'-Biphenyl)-2-carboxamide, N-(4-(4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)phenyl)- AC1L45SX AM20090722 FT-0724257 N-[4-(2-methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamide PDSP2_001718 [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]- BDBM85095 D07748 IKENVDNFQMCRTR-UHFFFAOYSA-N N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide Vaprisol (TN) DB00872 LS-187117 NSC_151171 YM087 0NJ98Y462X AKOS015917893 BC220859 Conivaptan (INN) GTPL2203 N-[4-(2-methyl4,5-dihydro-3H-imidazo[5,4-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamide SCHEMBL49815 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide CAS_151171 D0VU2X L001073 NCGC00345881-02 YM 087 AB01565868_02 AKOS027326517 CHEMBL1755 DTXSID80175220 N-(4-(2-methyl-1,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide PDSP1_001735 ZINC12503187 210101-16-9 [ Show all ]
Inchi Key	IKENVDNFQMCRTR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H26N4O2/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37)
PubChem CID	151171
ChEMBL	CHEMBL1755
IUPHAR	2203
BindingDB	85095
DrugBank	DB00872
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
135243	Oxytocin receptor	P70536	Oxtr	Rattus norvegicus (Rat)	388
135240	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418
556004	Vasopressin V1a receptor	P30560	Avpr1a	Rattus norvegicus (Rat)	424
135242	Vasopressin V1b receptor	P48974	Avpr1b	Rattus norvegicus (Rat)	425
135239	Vasopressin V2 receptor	P30518	AVPR2	Homo sapiens (Human)	371
135241	Vasopressin V2 receptor	Q00788	Avpr2	Rattus norvegicus (Rat)	371

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