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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2036315
Molecular formula	C26H32N2O5S
IUPAC name	4-[2-[(2R)-2-[(E,3S)-3-hydroxy-4-[3-(pyridin-3-ylmethoxy)phenyl]but-1-enyl]-5-oxopyrrolidin-1-yl]ethylsulfanyl]butanoic acid
Molecular weight	484.611
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	2.3
Synonyms	BDBM50385125 SCHEMBL10210629
Inchi Key	JSGJBDBGONKGOZ-UCQVOXAISA-N
Inchi ID	InChI=1S/C26H32N2O5S/c29-23(16-20-4-1-6-24(17-20)33-19-21-5-2-12-27-18-21)10-8-22-9-11-25(30)28(22)13-15-34-14-3-7-26(31)32/h1-2,4-6,8,10,12,17-18,22-23,29H,3,7,9,11,13-16,19H2,(H,31,32)/b10-8+/t22-,23+/m0/s1
PubChem CID	57894065
ChEMBL	CHEMBL2036315
IUPHAR	N/A
BindingDB	50385125
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
158727	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
158724	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
158726	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
158725	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488
158728	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513

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