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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	59880-97-6
Molecular formula	C21H31N3O5S
IUPAC name	(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid
Molecular weight	437.555
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	1.5
Synonyms	fMLP (misnomer but widely used) HY-P0224 MolPort-003-934-280 PRQROPMIIGLWRP-BZSNNMDCSA-N 34065-EP2295055A2 C-22333 D0M0YH formyl-Met-Leu-Phe L-Phenylalanine, N-formyl-L-methionyl-L-leucyl- N-Formyl-Met-Leu-Phe, >=97% (HPLC) ZINC4099172 CHEBI:53490 F-Met-leu-phe fMLF GTPL1022 MLS001361389 N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE (S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-butyrylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid B6888 Chemotactic peptide For-Met-Leu-Phe-OH KS-000019CN N-Formyl-L-methionyl-L-leucyl-L-phenylalanine SCHEMBL39529 34065-EP2311453A1 C11596 D0XF0A formyl-methionyl-leucyl-phenylalanine LS-193196 N-Formyl-Met-Leu-Phe, BioXtra, >=99.0% (TLC) (2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid AC1L9EDZ fMet-Leu-Phe FMLP HMS2235B23 MLS002207097 n-formylmethionine-leucine-phenylalanine BDBM50050937 CS-6489 Formyl met leu phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-Met-Leu-Phe SMR000857394 CC-25639 DTXSID9041077 fMetLeuPhe FT-0640642 MFCD00036780 N-Formyl-methionyl-leucyl-phenylalanine (S)-2-((S)-2-((S)-2-Formamido-4-(methylthio)butanamido)-4-methylpentanamido)-3-phenylpropanoic acid AKOS024456858 CHEMBL267179 [ Show all ]
Inchi Key	PRQROPMIIGLWRP-BZSNNMDCSA-N
Inchi ID	InChI=1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1
PubChem CID	443295
ChEMBL	CHEMBL267179
IUPHAR	1022
BindingDB	50050937
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
267107	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350
554591	fMet-Leu-Phe receptor	P33766	Fpr1	Mus musculus (Mouse)	364
452279	Formyl peptide receptor-related sequence 1	O08790	Fpr-s1	Mus musculus (Mouse)	351
267109	N-formyl peptide receptor 2	P25090	FPR2	Homo sapiens (Human)	351
267110	N-formyl peptide receptor 3	P25089	FPR3	Homo sapiens (Human)	353

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