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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1223814
Molecular formula	C27H32N4O4
IUPAC name	N-(cyclopropylmethyl)-2-[6-(3-morpholin-4-ylpropoxy)-4-oxo-2-phenylquinazolin-3-yl]acetamide
Molecular weight	476.577
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.6
Synonyms	BDBM50325847 N-(cyclopropylmethyl)-2-(6-(3-morpholinopropoxy)-4-oxo-2-phenylquinazolin-3(4H)-yl)acetamide
Inchi Key	VEDIIFYRKAULFT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32N4O4/c32-25(28-18-20-7-8-20)19-31-26(21-5-2-1-3-6-21)29-24-10-9-22(17-23(24)27(31)33)35-14-4-11-30-12-15-34-16-13-30/h1-3,5-6,9-10,17,20H,4,7-8,11-16,18-19H2,(H,28,32)
PubChem CID	46934434
ChEMBL	CHEMBL1223814
IUPHAR	N/A
BindingDB	50325847
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
352900	Oxytocin receptor	P30559	OXTR	Homo sapiens (Human)	389
352899	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418
352898	Vasopressin V1b receptor	P48974	Avpr1b	Rattus norvegicus (Rat)	425
352902	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424
352901	Vasopressin V2 receptor	P30518	AVPR2	Homo sapiens (Human)	371

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