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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1,3,7-trimethyl-5-((2-oxo-2-(piperidin-1-yl)ethyl)thio)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione
Molecular formula	C16H21N5O3S
IUPAC name	1,3,7-trimethyl-5-(2-oxo-2-piperidin-1-ylethyl)sulfanylpyrimido[4,5-d]pyrimidine-2,4-dione
Molecular weight	363.436
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	1.0
Synonyms	F0654-0013 AKOS024592576 SCHEMBL1279533 CHEMBL3962122 ZINC4138740 852167-87-4 MCULE-6247397479 CCG-30066 SR-01000132146 1,3,7-trimethyl-5-(2-oxo-2-piperidin-1-ylethyl)sulfanylpyrimido[4,5-d]pyrimidine-2,4-dione EU-0093472 AC1NDYHV MolPort-003-040-878 SR-01000132146-1 [ Show all ]
Inchi Key	VIFDCVBUAQDKDB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H21N5O3S/c1-10-17-13-12(15(23)20(3)16(24)19(13)2)14(18-10)25-9-11(22)21-7-5-4-6-8-21/h4-9H2,1-3H3
PubChem CID	4608957
ChEMBL	CHEMBL3962122
IUPHAR	N/A
BindingDB	211237
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521087	Taste receptor type 2 member 14	Q9NYV8	TAS2R14	Homo sapiens (Human)	317

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