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GPCR-I-TASSER results for job id P47804

[Click on P47804_results.tar.bz2 to download the tarball file including all modeling results listed on this page]

  Submitted Sequence

>P47804
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLAL
ADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTR
SQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTM
SFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVT
SISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK

  Predicted Secondary Structure

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |           
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
PredictionCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSSCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSSSSCCCCCCHHHHHHHHHHHHHHHHHHHHHHSSSSSSSSSCCCSSSSSSSCCCCCCCCCCCSSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
Conf.Score999999999988789999999999999999987886465345058889689999999999999999985999999991988787668889999999999999999999999861788489877777899999999999999997455267789972990799982169886751151674638899999999999999999999989888661342133212330899999999978855479999999999999999887797553299999999998599888766789

  Predicted Solvent Accessibility

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |           
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
Prediction846444323313330022013313320331333132001000123302302010010103101311331330010033221110330022102100200110130000002100100022331343200000020133023003103211220223330000000033734412000000023123311200120132002102423432321133020000002112210000001343402010003003000100020010000004301400141033434666668
Values range from 0 (buried residue) to 9 (highly exposed residue)

   Predicted normalized B-factor


  Top 10 templates used by GPCR-I-TASSER

Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |           
Sec.Str
Seq		CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSSCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSSSSCCCCCCHHHHHHHHHHHHHHHHHHHHHHSSSSSSSSSCCCSSSSSSSCCCCCCCCCCCSSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSSHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
14zwjA 0.21 0.29 1.00 2.51Download SPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHYFVFGPTGCNLQGFFATLGGEIALWSLVVLAIERYVVVCKPMRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQATTQKAEKEVTRMVIIYVIAFLICWVPYQGSCFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKNVIFKKV
21gzmA 0.23 0.26 0.98 4.13Download ---EAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHENNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKN---DD-
32z73A 0.24 0.27 1.00 3.76Download VHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILGFFGPILIIFFCYFNIVAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPLTCCQFDDKE
44djh 0.20 0.27 0.92 1.49Download -----------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKATPLKAKIINICIWLLSSSVGISAIVLGGTKVRDVDVIECSLQFPDDDYSDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGKDRRITRVFVVCWTPIHIFILVEALGSA---ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------
54djh 0.19 0.27 0.92 1.14Download -----------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKRTPLKAKIINICIWLLSSSVGISAIVLGGTKVRDVDVIECSLQFPDDDYSDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA---ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------
65tjvA 0.18 0.25 0.93 2.88Download --MDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNC---EKLQSVCSDIFP----HIDETYLMFWIGVTSVLLLFIVYAYMYILWKARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-----------
74djh 0.20 0.27 0.91 1.69Download -------------AIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDLKAKIINICIWLLSSSVGISAIVLGGTKVREVDVIECSLQFPDDDYWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLTRLVLVVVAVFVVCWTPIHIFILVEALGS---AALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------
81u19A 0.22 0.27 1.00 3.85Download VVRSPPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDE
94n6hA 0.16 0.20 0.97 3.04Download ---SPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDG-AVVCMLQFPSPSYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVKEKDRSLRRITGAFVVCWAPIHIFVIVWTLVDIDRRDVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCG------
101l9hA 0.22 0.28 1.00 4.09Download FSNEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDST
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=0.93 (Read more about C-score)
  • Estimated TM-score = 0.84±0.08
  • Estimated RMSD = 4.2±2.8Å

  • Download Model 2
  • C-score = -1.67

  • Download Model 3
  • C-score = -3.38

  • Download Model 4
  • C-score = -4.20

  • Download Model 5
  • C-score = -5



    • [Click on P47804_results.tar.bz2 to download the tarball file including all modeling results listed on this page]


     Please cite the following articles when you use the GPCR-I-TASSER server:
    J Zhang, J Yang, R Jang, Y Zhang. GPCR-I-TASSER: A hybrid approach to G protein-coupled receptor structure modeling and the application to the human genome, Structure, 23: 1538-1549, 2015.