Detailed GPCR-I-TASSER Statistics for Q8NH56

Submitted Sequence

>sp|Q8NH56|O52N5_HUMAN
MPLFNSLCWFPTIHVTPPSFILNGIPGLERVHVWISLPLCTMYIIFLVGNLGLVYLIYYE
ESLHHPMYFFFGHALSLIDLLTCTTTLPNALCIFWFSLKEINFNACLAQMFFVHGFTGVE
SGVLMLMALDRYVAICYPLRYATTLTNPIIAKAELATFLRGVLLMIPFPFLVKRLPFCQS
NIISHTYCDHMSVVKLSCASIKVNVIYGLMVALLIGVFDICCISLSYTLILKAAISLSSS
DARQKAFSTCTAHISAIIITYVPAFFTFFAHRFGGHTIPPSLHIIVANLYLLLPPTLNPI
VYGVKTKQIRKSVIKFFQGDKGAG

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |    
Sequence MPLFNSLCWFPTIHVTPPSFILNGIPGLERVHVWISLPLCTMYIIFLVGNLGLVYLIYYEESLHHPMYFFFGHALSLIDLLTCTTTLPNALCIFWFSLKEINFNACLAQMFFVHGFTGVESGVLMLMALDRYVAICYPLRYATTLTNPIIAKAELATFLRGVLLMIPFPFLVKRLPFCQSNIISHTYCDHMSVVKLSCASIKVNVIYGLMVALLIGVFDICCISLSYTLILKAAISLSSSDARQKAFSTCTAHISAIIITYVPAFFTFFAHRFGGHTIPPSLHIIVANLYLLLPPTLNPIVYGVKTKQIRKSVIKFFQGDKGAG
Prediction CCCCCCCCCCCCCCCCCCCSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCSSSSCCHHHHHHHHHHHHHCCCCCC
Conf.Score 997564423689987552114779999866799999999999999999999999998647875426699999899999999998569999999826998788878999999999999999999999980316862665457602868999999999999999999889999825899998968873320066788843794154599999999999999999999999999998078898898999772899999999999999999500045888899336689999985277553570110556999999999971266899

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |    
Sequence MPLFNSLCWFPTIHVTPPSFILNGIPGLERVHVWISLPLCTMYIIFLVGNLGLVYLIYYEESLHHPMYFFFGHALSLIDLLTCTTTLPNALCIFWFSLKEINFNACLAQMFFVHGFTGVESGVLMLMALDRYVAICYPLRYATTLTNPIIAKAELATFLRGVLLMIPFPFLVKRLPFCQSNIISHTYCDHMSVVKLSCASIKVNVIYGLMVALLIGVFDICCISLSYTLILKAAISLSSSDARQKAFSTCTAHISAIIITYVPAFFTFFAHRFGGHTIPPSLHIIVANLYLLLPPTLNPIVYGVKTKQIRKSVIKFFQGDKGAG
Prediction 644322112213343311102000001213202000110120122023212100000201510010001000300010000002000020000000204403040000001200310130100001002000000021010000002410010000003212011202100021022044200000001021001000230300011002003313332231032011100200020024601320120010010001003231331010000142400110002102310030033003000020340041003002444778

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |    
Sec.Str
Seq		CCCCCCCCCCCCCCCCCCCSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCSSSSCCHHHHHHHHHHHHHCCCCCC
MPLFNSLCWFPTIHVTPPSFILNGIPGLERVHVWISLPLCTMYIIFLVGNLGLVYLIYYEESLHHPMYFFFGHALSLIDLLTCTTTLPNALCIFWFSLKEINFNACLAQMFFVHGFTGVESGVLMLMALDRYVAICYPLRYATTLTNPIIAKAELATFLRGVLLMIPFPFLVKRLPFCQSNIISHTYCDHMSVVKLSCASIKVNVIYGLMVALLIGVFDICCISLSYTLILKAAISLSSSDARQKAFSTCTAHISAIIITYVPAFFTFFAHRFGGHTIPPSLHIIVANLYLLLPPTLNPIVYGVKTKQIRKSVIKFFQGDKGAG
13emlA 0.15 0.20 0.86 2.28Download ---------------------------IM-GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQN-VTNYFVVSLAAADIAVGVLAIPFAITIST--GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACL-----------FEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFFC----PDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
25tgzA 0.22 0.24 0.83 2.09Download -----------------------------SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGS-LAVADLLGSVIFVYSFIDF-HVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLL-------GWNCEKLQSVC---------SDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAPDQARIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-------
35tgzA 0.21 0.24 0.88 1.81Download GGRGENFMDIECFMVLNP-----------SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRRPSY-HFIGSLAVADLLGSVIFVYSFIDFH-VFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLCEKLQSVCSD-IFPHID------------------KTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHAQARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-------
44ib4 0.17 0.23 0.87 1.53Download -------------------------EEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLM-SLAVADLLVGLFVMPIALLTIMEAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVWLISIGIAIPVPIKG-IET----N-PNNITCVLTK-------E--RFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAADSNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR--
53uonA 0.17 0.19 0.84 1.12Download ----------------------------TFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLF-SLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQF--IVGVRTVEDGECYIQFF---------SNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSR----REKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTV-WTIGYWLCYINSTINPACYALCNATFKKTFKHLLM------
63emlA 0.16 0.20 0.85 2.54Download -----------------------------MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVV-SLAAADIAVGVLAIPFAITIST--GFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVV-----------PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFFC----PDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQ
73d4s 0.16 0.17 0.60 1.70Download --------------------------------VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITS-LACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWY----RATHQEAINCYAE----ETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKR----------------------------------------------------------------------------------------
84buoA 0.18 0.18 0.89 2.96Download ----------------------NDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVDYYLGS-LALSDLLILLLAMPVELYNFIWVHHPWAFAGCRGYYFLRDACTYATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPGGLVCTPIV------DTATLKVVIQVNTFMSFLFPMLVASILNTVIANKLTVMVHQPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDHYFYMLTNALVYVSAAINPILYNLVSANFRQVFLSTL-------
95tgzA 0.20 0.24 0.89 3.00Download -----GGRGENFMDI--ECFMVLN----PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK-DSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLG--------NCEKLQSVC---------SDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKA-APDQARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-------
104gpoA 0.15 0.19 0.86 4.44Download ---------------------------LQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNL-FITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPG--------CCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVP-DWLFVAFNWLGYANSAMNPIIYC-RSPDFRKAFKRL--------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.68 (Read more about C-score)
  • Estimated TM-score = 0.63±0.14
  • Estimated RMSD = 7.9±4.4Å

  • Download Model 2
  • C-score = -1.03

  • Download Model 3
  • C-score = -2.42

  • Download Model 4
  • C-score = -3.95

  • Download Model 5
  • C-score = -1.55


    • [Click on Q8NH56_results.tar.bz2 to download the tarball file including all modeling results listed on this page]