Detailed GPCR-I-TASSER Statistics for Q8TDU5

Submitted Sequence

>sp|Q8TDU5|VNRL4_HUMAN
MEMTKLFSYIVIKNVYYPQVSFGISANTFLLLFHIFTFAYTHRLKPIDMTISHLPLIHIL
LLFTQAILVSSDLFESWNIQNNDLKCKIITFLNRVMRGVSICTTCLLSVLQAITISPSTS
FLEKFKHISANHTLGFILFSWVLNMFITNNLLLFIVPTPNRIGASLLFVTEHCYVLPMSY
THRSLFFILMVLRDVIFIGLMVLSSGYG

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |        
Sequence MEMTKLFSYIVIKNVYYPQVSFGISANTFLLLFHIFTFAYTHRLKPIDMTISHLPLIHILLLFTQAILVSSDLFESWNIQNNDLKCKIITFLNRVMRGVSICTTCLLSVLQAITISPSTSFLEKFKHISANHTLGFILFSWVLNMFITNNLLLFIVPTPNRIGASLLFVTEHCYVLPMSYTHRSLFFILMVLRDVIFIGLMVLSSGYG
Prediction CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCSSSSSSSHHHHCCCHHHHHHHHHHHHSSSSCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCSSSSSCCCCCCCCCCSSCCCCCSSSCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Conf.Score 9701605999999999999999999999999999999983889994999999999999999999648999999964567589875167887607656530657888888722894289638888888567203558999999999986040389866885665267101306825077378888888999897899999998725799

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |        
Sequence MEMTKLFSYIVIKNVYYPQVSFGISANTFLLLFHIFTFAYTHRLKPIDMTISHLPLIHILLLFTQAILVSSDLFESWNIQNNDLKCKIITFLNRVMRGVSICTTCLLSVLQAITISPSTSFLEKFKHISANHTLGFILFSWVLNMFITNNLLLFIVPTPNRIGASLLFVTEHCYVLPMSYTHRSLFFILMVLRDVIFIGLMVLSSGYG
Prediction 6743312230111111331133233233303321010002444331110012101311221031233230020011343333311000000111132232010001012300000013323034023302220113001203211313330023030333333333333321111133333211110311333323112123221328

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |        
Sec.Str
Seq		CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCSSSSSSSHHHHCCCHHHHHHHHHHHHSSSSCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCSSSSSCCCCCCCCCCSSCCCCCSSSCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MEMTKLFSYIVIKNVYYPQVSFGISANTFLLLFHIFTFAYTHRLKPIDMTISHLPLIHILLLFTQAILVSSDLFESWNIQNNDLKCKIITFLNRVMRGVSICTTCLLSVLQAITISPSTSFLEKFKHISANHTLGFILFSWVLNMFITNNLLLFIVPTPNRIGASLLFVTEHCYVLPMSYTHRSLFFILMVLRDVIFIGLMVLSSGYG
14grvA 0.14 0.18 0.95 1.02Download LDNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLAR-----KSLQTVHYHLGSLALSDLLILLLAMPVELYNFIWVHPWAFGDAGCRGYYFLRDACTYATALNVASLSVARYLAIHPFKAKTL----MSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSADGTHPGGL-VCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVI
25x33A 0.12 0.23 0.89 1.43Download ------FIPLLAMILLSVSMVVGLPGNTFVVW---SILKRMRKRSVTALMVLNLALADLAVLLT--APFFLHFLTWGTWSFGLAGCRLCHYICGVSMYASVLLITAMSLDRSLAVA---SPFLSQKVRTKTAARWLLVGIWGASFLLATPVLAFRKVVKLTNETD------LCLAVYPSDRHKAFHLLFEAF-TGFVVPFLIVVASY-
35t1aA 0.16 0.21 0.90 1.28Download ---VKQIGAQLLPPLYSLVFIFGFVGNMLVVLILINC--KKLK-CLTDIYLLNLAISDLLFLIT--LPLWAHSAAN-EWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIV-HAVFALKART--VTFGVVTSVITWLVAVFASVPGIIFT--KQKEDSVYV------CGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGI
45t1a 0.16 0.21 0.90 1.55Download ---VKQIGAQLLPPLYSLVFIFGFVGNMLVVLILIN---CKKLKCLTDIYLLNLAISDLLFLIT--LPLWAHSA-ANEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFAL---KARTVTFGVVTSVITWLVAVFASVPGIIFTKQKE--------DSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGI
55x33 0.13 0.17 0.92 1.22Download ---SNTFIPLLAMILLSVSMVVGLPGNTFVVWSILK---RMRKRSVTALMVLNLALADLAVLL--TAPFFLHFLTWGTWSFGLAGCRLCHYICGVSMYASVLLITAMSLDRSLAVASPF--LS-QKVRTKTAARWLLVGIWGASFLLATPVLAFRKVVKL------TNETDLCLAVYPSDRHKAFHLLEAFTGFVVPFLIVVASYADI
64grvA 0.14 0.18 0.95 1.15Download --NTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLAR----KSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVARYLAICHPFKAKTL---MSRSRTKKFISAIWLASALLAIPMLFTMGL-QNRSADGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVI
74xnv 0.15 0.22 0.88 1.67Download -----GFQFYYLPAVYILVFIIGFLGNSVAIWMF---VFHMKPWSGISVYMFNLALADFLYVLT--LPALIFYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYP-KSLGRLKK---KNAICISVLVWLIVVVAISPILFYSGTGVRK------NKTITCYDTTSDEYLYFIYSMTTVAMFCVPLVLILG-----
84dklA 0.18 0.24 0.88 1.18Download -----MVTAITIMALYSIVCVVGLFGNFLVMYV---IVRYTKMKTATNIYIFNLALADALATST--LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFR---TPRNAKIVNVCNWILSSAIGLPVMFMIDCTLTFSH-------------PTWYWENLLKICVFIFAFIMPVLIITVCYGLM
95unfA 0.16 0.16 0.71 1.14Download -------HLDAIPILYYIIFVIGFLVNIVVVTLFCCQ----GPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRY-DWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVYP-------FPWQA----SYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA-----CIMA--------------------------------
106b73A 0.16 0.19 0.90 1.75Download LGSISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIR----YTKMKTTNIYIFNLALADALV--TTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVC--HPVKAL-DFRTPLKAKIINICIWLLSSSVGISAIVLGG--------TKVRDVIECSLQFPDDLFMKICVFIFAF--VIPVLIIIVC--YT
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.23 (Read more about C-score)
  • Estimated TM-score = 0.68±0.12
  • Estimated RMSD = 5.9±3.7Å

  • Download Model 2
  • C-score = -3.62

  • Download Model 3
  • C-score = -6.75

  • Download Model 4
  • C-score = -7.19

  • Download Model 5
  • C-score = -7.05


    • [Click on Q8TDU5_results.tar.bz2 to download the tarball file including all modeling results listed on this page]