Detailed GPCR-I-TASSER Statistics for Q9H228

Submitted Sequence

>sp|Q9H228|S1PR5_HUMAN
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
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Sequence MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
Prediction CCCCCCCCCCCCCCSSCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCSSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCSSSSSCCCCCCSSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCSSCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 98666899987642122121579878988898339999999999999999998998414312268999589999999999999999999999999763531516701888711678879999999999999859880587769860387889988999999999999999862877799831478404786055763589999999999999999999999999997436776664201356688999999999999999999999999999999779877873479999999999999996999993799999999999578888999898887777651105898333379877788789888997778998988778999988777666799998

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
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Sequence MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
Prediction 74442255232331010010211434435322211000000000100210331330000000103300000000000001000101212111000103120110000000100000000000120000001000000010121431332000000000011012102100000012343610000001332000000022133112000200010000003003303434544444443343343011001000000200100010000000000003231000001000001000100021000100104400300130000022234446633544433354444444433443545344363444454444353444443434434433454668

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340                 360                 380
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Sec.Str
Seq		CCCCCCCCCCCCCCSSCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCSSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCSSSSSCCCCCCSSSSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCSSCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
15tjvA 0.27 0.22 0.72 2.73Download ------------------ENFMDIECFMVLNP-SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKA-------------GKRAMSFSDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-----------------------------------------------------------------------------
22ziy 0.16 0.19 0.89 1.51Download -DLRDNETWWYNPSIIVHPHWRE----FDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNFPLMTICFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTVLCNCSFDYISTTRSNILCMILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNALRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWV--TPYAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDK-E--TEDDKDAE-------T-----------------EIPAGESSDAAP--------SADAAQMK
34z34A 0.31 0.28 0.78 3.76Download -----EPQCFYNESIAFFYNRSGKHLATEWNT--VSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETKTTRNAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKF--FLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-----------------------------------------------------------------------------
45tgzA 0.27 0.22 0.73 3.32Download --------------GGRGENFMDIECFMVLNPS-QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKRVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHI--DKTYLMFWIGVVSVLLLFIVYAYMYILWKAHSHA--------------PDQARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNK-LIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-----------------------------------------------------------------------------
54z34 0.31 0.28 0.78 1.57Download ----NEPQCFYNESIAFFYNRSGKHLATEW--NTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFR-MQLHTRMNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLKAMKDFIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQC--D-VLAEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG----------------------------------------------------------------------------
64ib4 0.22 0.20 0.75 1.18Download ----------------------------EEQ-GNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMAMWPLPLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIKKPIQANYNSRATAFIKITVVWLISIGIAIPPIKGIETNPNNITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLTIHALQKKAADLEDNWETLAYIQKYLQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYR------------------------------------------------------------------------
75tjvA 0.27 0.22 0.72 2.92Download -------------------NFMDIECFMV-LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAG-------------KRAMSFSDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNK-LIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-----------------------------------------------------------------------------
84z34 0.32 0.28 0.77 1.80Download ----------YNESIAFFYNRSGKHLATEW--NTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVADLEDNWETLNAMKAYIQKYLRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDV--LAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILG----------------------------------------------------------------------------
91u19A 0.18 0.20 0.83 4.75Download -----MNGTEGPNFYVPFSNKTGVVRSPFEAPQWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYGMQCSCGIDYYTPHSFVIYMFVVHFIIPLIVIFFCYGQLVFT----------VKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAF-FAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTESQVAPA---------------------------------------------------
105tjvA 0.27 0.22 0.72 2.96Download ------------------ENFMDIECFMVLNP-SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLAAIDRYISIHRPLAYKIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKA-------------GKRAMSFSDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF-----------------------------------------------------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: HHSEARCH2   3: FFAS-3D   4: SPARKS-X   5: HHSEARCH2   6: HHSEARCH I   7: Neff-PPAS   8: HHSEARCH   9: pGenTHREADER   10: wdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-1.09 (Read more about C-score)
  • Estimated TM-score = 0.58±0.14
  • Estimated RMSD = 9.3±4.6Å

  • Download Model 2
  • C-score = -1.46

  • Download Model 3
  • C-score = -1.63

  • Download Model 4
  • C-score = -1.36

  • Download Model 5
  • C-score = -3.01


    • [Click on Q9H228_results.tar.bz2 to download the tarball file including all modeling results listed on this page]