GPCR-I-TASSER results for Q9Y5P0

[Click on Q9Y5P0_results.tar.bz2 to download the tarball file including all modeling results listed on this page]

  Submitted Sequence

>Q9Y5P0
MWYNNSAGPFLLTGFLGSEAVHYRISMSFFVIYFSILFGNGTLLVLIWNDHSLHEPMYYF
LAMLADTDLGMTFTTMPTVLGVLLLDQREIAHAACFTQSFIHSLAIVESGILLVLAYDCF
IAIRTPLRYNCILTNSRVMNIGLGVLMRGFMSILPIILSLYCYPYCGSRALLHTFCLHQD
VIKLACADITFNHIYPIIQTSLTVFLDALIIIFSYILILKTVMGIASGQEEAKSLNTCVS
HISCVLVFHITVMGLSFIHRFGKHAPHVVPITMSYVHFLFPPFVNPIIYSIKTKQIQRSI
IRLFSGQSRA

  Predicted Secondary Structure

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |          
MWYNNSAGPFLLTGFLGSEAVHYRISMSFFVIYFSILFGNGTLLVLIWNDHSLHEPMYYFLAMLADTDLGMTFTTMPTVLGVLLLDQREIAHAACFTQSFIHSLAIVESGILLVLAYDCFIAIRTPLRYNCILTNSRVMNIGLGVLMRGFMSILPIILSLYCYPYCGSRALLHTFCLHQDVIKLACADITFNHIYPIIQTSLTVFLDALIIIFSYILILKTVMGIASGQEEAKSLNTCVSHISCVLVFHITVMGLSFIHRFGKHAPHVVPITMSYVHFLFPPFVNPIIYSIKTKQIQRSIIRLFSGQSRA
PredictionCCCCCCCCCCSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSCCCCCCCCCHHHHHHHHHHHHCCCCCCCCSCSCCHHHHHHHHHHHHCCCCCC
Conf.Score9999977400257899976689999999999999999999999998867887543389999999999998998549999999836998788878999999999999999999999803168516664575018789999999999999999999899999348999989578844420656788357845878999999999999989999999999999980788987889987617999999999999899885035678989935889999998427755368010155699999999995336799

  Predicted Solvent Accessibility

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |          
MWYNNSAGPFLLTGFLGSEAVHYRISMSFFVIYFSILFGNGTLLVLIWNDHSLHEPMYYFLAMLADTDLGMTFTTMPTVLGVLLLDQREIAHAACFTQSFIHSLAIVESGILLVLAYDCFIAIRTPLRYNCILTNSRVMNIGLGVLMRGFMSILPIILSLYCYPYCGSRALLHTFCLHQDVIKLACADITFNHIYPIIQTSLTVFLDALIIIFSYILILKTVMGIASGQEEAKSLNTCVSHISCVLVFHITVMGLSFIHRFGKHAPHVVPITMSYVHFLFPPFVNPIIYSIKTKQIQRSIIRLFSGQSRA
Prediction7534243120200000323410110023023222213332320000010043002000200110011011002012020000001433402030011012012103301300010000000000210100000033000000000122110213021320200210462201000010220030002203001210232033333332310320122002000303056013200100000000020133213210000233341233010000121223113300300002033014002300243678
Values range from 0 (buried residue) to 9 (highly exposed residue)

   Predicted normalized B-factor


  Top 10 templates used by GPCR-I-TASSER

Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |          
Sec.Str
Seq		CCCCCCCCCCSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCSSCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCSCCCCCCCCCHHHHHHHHHHHHCCCCCCCCSCSCCHHHHHHHHHHHHCCCCCC
MWYNNSAGPFLLTGFLGSEAVHYRISMSFFVIYFSILFGNGTLLVLIWNDHSLHEPMYYFLAMLADTDLGMTFTTMPTVLGVLLLDQREIAHAACFTQSFIHSLAIVESGILLVLAYDCFIAIRTPLRYNCILTNSRVMNIGLGVLMRGFMSILPIILSLYCYPYCGSRALLHTFCLHQDVIKLACADITFNHIYPIIQTSLTVFLDALIIIFSYILILKTVMGIASGQEEAKSLNTCVSHISCVLVFHITVMGLSFIHRFGKHAPHVVPITMSYVHFLFPPFVNPIIYSIKTKQIQRSIIRLFSGQSRA
13uonA 0.16 0.19 0.86 1.92Download ---------------------VVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFF-----------SNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRREK----KVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLL------
24iaqA 0.18 0.21 0.87 1.89Download ----------YIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTG--RWTLVCDFWLSSDITCCTASIWHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPP------FFWRQASE---------------CVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIMAARERKATKTLGIILGAFIVCWLPFFIISLVMPIHL-----AIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFK---
33emlA 0.18 0.26 0.89 2.37Download -----------------IM-GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIST--GFCAAHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACL-----------FEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFFC---PDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLR
43uonA 0.16 0.17 0.89 2.56Download ------------------TFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLLDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVG--VRTVEDGECYIQFF---------SNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRINPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM-----
54bvnA 0.17 0.21 0.89 2.05Download -----------------LQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLVLCVTASVETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMH----WWRDEDPQALKCYQ----DPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKE----MREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPKWLFVAFNWLGYANSAMNPIILC-RSPDFRKAFKRLLA-----
63emlA 0.17 0.26 0.89 2.77Download -------------------MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTG--FCAACHGCLFIACVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGGCGEGQVACLFEDVV-----------PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDC---SHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLR
72r4rA 0.21 0.22 0.65 2.97Download -------------------------GIVMSLIVLAIVFGNVLVITAIA-FERLQTVTNYFITSLACADLVMGLAVVPFG-----------------FWTSIDLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTS----------------------------------------------SIVSFYVPLVIMVFVYSRVFQEAKRIDKSLKEHKALKTLGIIMGTFTLCWLPFFI-------------------LNWIGYVNSGFNPLIYC-RSPDFRIAFQELLCLRRS-
84buoA 0.15 0.19 0.93 2.81Download ---NSDL------DVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVDYYLGSLALSDLLILLLAMPVELYNFIWVHHPWAFAGCRGYYFRDACTYATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPGGLVCTPIV------DTATLKVVIQVNTFMSFLFPMLVASILNTVIANKLTVMVHQPGRVQALRRGVLVLRAVVIAFVVVRRLMFCYISDEQWTYHYFYMLTNALVYVSAAINPILYNLVSANFRQVFLSTL------
93emlA 0.16 0.26 0.88 3.09Download -----------------I--GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISF----CAACHGCLFIACFVLVLTQSSIFSLLAI-DRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPML---------WNNCGQSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLPLHIINCFTFF---CPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHRQ-
103emlA 0.18 0.26 0.89 3.99Download IMGS------------------SVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAI--TISTGFCAACHGCLFIACFLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLNCGQSQGCGEGQVACLFEDVVPMNYMVYFNFFACVL-----------VPLLLMLGVYLRIFLAARRQLVHAAKSLAIIVGLFALCWLP-LHIINCFTFF--CPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVRQ
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: FFAS-3D   2: SPARKS-X   3: MUSTER   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: PROSPECT2   

  Top 5 Models predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.08 (Read more about C-score)
  • Estimated TM-score = 0.70±0.12
  • Estimated RMSD = 6.4±3.9Å

  • Download Model 2
  • C-score = -1.20

  • Download Model 3
  • C-score = -1.73

  • Download Model 4
  • C-score = -2.23

  • Download Model 5
  • C-score = -1.82




    •  Please cite following articles when you use the GPCR-I-TASSER server:
    J Zhang, J Yang, R Jang, Y Zhang. Hybrid structure modeling of G protein-coupled receptors in the human genome, submitted (2015).