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I-TASSER I-TASSER-MTD C-I-TASSER QUARK C-QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH Threpp BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign CR-I-TASSER GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
sctr_rat V38M sctr_rat C46 sctr_rat C46A
sctr_rat C46S sctr_rat A63M sctr_rat C66
sctr_rat C66A sctr_rat C66S sctr_rat D71A
sctr_rat D71E sctr_rat D71H sctr_rat D71N
sctr_rat D71R sctr_rat C75 sctr_rat C75A
sctr_rat C75S sctr_rat C89 sctr_rat C89A
sctr_rat C89S sctr_rat M95I sctr_rat R105D
sctr_rat R105L sctr_rat C107 sctr_rat C107A
sctr_rat C107S sctr_rat D120 sctr_rat L121M
sctr_rat C123 sctr_rat C123A sctr_rat C123S
sctr_rat E133D sctr_rat K143L sctr_rat K143Q
sctr_rat H178R sctr_rat C208 sctr_rat C208A
sctr_rat C208S sctr_rat H211L sctr_rat K212S
sctr_rat C215 sctr_rat K216A sctr_rat K216Q
sctr_rat E281N sctr_rat E281Q sctr_rat E281V
sctr_rat C285 sctr_rat E363A sctr_rat D364A
sctr_rat E367A vipr1_human C37G vipr1_human C50G
vipr1_human C63G vipr1_human D68G vipr1_human C72G
vipr1_human W73G vipr1_human C86G vipr1_human P87G
vipr1_human C105G vipr1_human W110G vipr1_human C122G
vipr1_human L199A  [Orientation Restraint] vipr1_human C208G vipr1_human C215A
vipr1_human C215G vipr1_human C215S vipr1_human C285A
vipr1_human C285G vipr1_human C285S vipr1_human W286A
vipr1_human W294A vipr1_mouse A212Q vipr2_human G87P
emr2_human S518A emr2_human S518T emr2_human S519A
gp128_human K758R gabr1_mouse S246A gabr1_mouse Y395A
gabr1_mouse D397A gabr1_mouse N398A gabr1_mouse E465A
gabr1_mouse E465D gabr1_mouse E465S gabr1_mouse D471R
gabr1_mouse K791W gabr1_rat C187A gabr1_rat C187S
gabr1_rat Q188A gabr1_rat E192A gabr1_rat C219A
gabr1_rat C245A gabr1_rat C245S gabr1_rat S246A


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