GPCR-I-TASSER model for Q6UPP1
(Q6UPP1_HUMAN Mu opioid receptor variant MOR1W OS=Homo sapiens GN=OPRM1 PE=2 SV=1)

Click to download model1.pdb

GPCR Sequence:

    >tr|Q6UPP1|Q6UPP1_HUMAN Mu opioid receptor variant MOR1W OS=Homo sapiens GN=OPRM1 PE=2 SV=1

Estimation of the GPCR-I-TASSER model for Q6UPP1

    C-score = 1.420
    TM-score = 0.910 (estimated)
    RMSD = 3.3 A (estimated)

    Here, C-score is a confidence score of the GPCR-I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of GPCR-I-TASSER simulations.

The top ten threading templates used by GPCR-I-TASSER


    J Zhang, J Yang, R Jang, Y Zhang, Novel hybrid approach to G protein-coupled receptor structure modeling and case study on human genome, submitted, 2014.

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